N-Ethylanilin Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
FARBLOSE FLüSSIGKEIT MIT CHARAKTERISTISCHEM GERUCH. VERFäRBT SICH BRAUN BEI KONTAKT MIT LICHT UND LUFT.
CHEMISCHE GEFAHREN
Beim Verbrennen Bildung giftiger Gase mit Stickstoffoxiden. Reagiert mit Oxidationsmitteln. Reagiert sehr heftig mit konzentrierter Salpetersäure unter Feuer- und Explosionsgefahr.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK nicht festgelegt (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation und durch Verschlucken.
INHALATIONSGEFAHREN
Nur ungenügende Angaben vorhanden über die Geschwindigkeit, mit der eine gesundheitsschädliche Konzentration in der Luft beim Verdampfen bei 20°C erreicht wird.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:
Die Substanz reizt die Augen und die Haut. Möglich sind Auswirkungen auf das Blut mit nachfolgender Methämoglobinbildung. Die Auswirkungen treten u.U. verzögert ein. ärztliche Beobachtung notwendig.
LECKAGE
Ausgelaufene Flüssigkeit in abdichtbaren Behältern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen. NICHT in die Kanalisation spülen. Persönliche Schutzausrüstung: Atemschutzfilter für organische Gase und Dämpfe.
R-Sätze Betriebsanweisung:
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
R33:Gefahr kumulativer Wirkungen.
S-Sätze Betriebsanweisung:
S28:Bei Berührung mit der Haut sofort abwaschen mit viel . . . (vom Hersteller anzugeben).
S37:Geeignete Schutzhandschuhe tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
N-Ethylaniline is yellow-brown oil with aweak fishy odor.
Occurrence
Polyethylene bottles used in intravenous solutions have been reported to be contaminated with N-ethylaniline from rubber parts of the closure (Ulsaker and Teien 1979). It has been reported that rubber containing N,N,-dithiodimorpholine accelerator of vulcanization can release N-ethylaniline into an aqueous media (Stankevich and Shurupova 1976). This compound has also been reported as a contaminant of cigarette smoke at a level of 55.8 ng per one U.S. 85 mm cigarette (Patrianakos and Hoffmann 1979).
Verwenden
N-Ethylaniline is used as an explosive stabilizer and indyestuff manufacture.
Vorbereitung Methode
Manufacture of N-ethylaniline is based on the reaction of aniline with alkyl halide or by heating aniline with ethyl alcohol under acidic conditions followed by purification (Windholz et al 1983).
Allgemeine Beschreibung
A dark liquid with an aromatic odor. Insoluble in water. Density 0.963 g / cm3. Toxic by skin absorption and inhalation of vapors. Evolves toxic fumes during combustion. Flash point 185°F.
Air & Water Reaktionen
Unstable to prolonged exposure to air and/or light. Insoluble in water.
Reaktivität anzeigen
N-Ethylaniline may react violently with nitric acid. May react with strong oxidizing agents. . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Hazard
Toxic by ingestion, inhalation, and skinabsorption.
Health Hazard
N-Ethylaniline is considered very hazardous in a fire situation, since it is highly toxic and readily absorbed by the inhalation, dermal and oral routes (HSDB 1988). Excessive exposure causes respiratory paralysis.
Brandgefahr
Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Industrielle Verwendung
N-Ethylaniline is used as an explosives stabilizer and as an intermediate in the manufacturing of dyes and pharmaceuticals (Northcott 1978).
Sicherheitsprofil
Poison by ingestion and intraperitoneal routes. Moderately toxic by an unspecified route. Mddly toxic by skin contact. An allergen. Flammable when exposed to heat or flame; can react with oxidizing materials. To fight fire, use dry chemical, CO2, foam. Hypergolic reaction with red fuming nitric acid. When heated to decomposition or on contact with acid or acid fumes it emits highly toxic fumes of aniline and NOx.
mögliche Exposition
This material is used as an intermediate in dyes, pharmaceuticals and explosives; in organicsynthesis.
Stoffwechsel
The metabolism of N-ethylaniline has been studied more as a tool to understanding microsomal drug metabolizing activity than as the central item of inquiry. However, the following have been clearly defined as metabolic products of N-ethylaniline: phenylhydroxylamine, N-hydroxyl, N-ethylaniline; N-ethyl-p-aminophenol; and aniline (Appel et al 1965; Heinze 1970; Hlavica 1970; Hlavica and Kiese 1969; Kampffmeyer and Kiese 1965; Kroeber et al 1970; Lange 1967 and Lange 1968). Nonmicrosomal metabolism has not been reported. Species shown capable of metabolism include rabbit, mouse, rat, dog, pig, and guinea pig with the proportions of the various metabolites often species dependent. Compounds similar to N-ethylaniline such as N-methyl-N-ethylaniline can form N-ethylaniline via demethylation (Gorrod et al 1975a,b).
Versand/Shipping
UN2272 N-Ethylaniline, Hazard Class: 6.1;Labels: 6.1-Poisonous materials
Inkompatibilitäten
May form explosive mixture with air.Decomposes on contact with light or air. Reacts with manymaterials. Neutralizes acids in exothermic reactions to formsalts plus water. Flammable gaseous hydrogen may be generated in combination with strong reducing agents such as hydrides, nitrides, alkali metals, and sulfides. Contact withstrong oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away fromalkaline materials; strong acids, such as nitric acid, cancause fire; explosions with formation of toxic vapors ofaniline and oxides of nitrogen; strong bases, isocyanates,halogenated organics, phenols (acidic), epoxides, anhydrides, and acid halides
N-Ethylanilin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Ethanol 2-Ethylanilin Tosylchlorid Anilin
Downstream Produkte
[2-[[4-[(2-Cyan-4-nitrophenyl)azo]phenyl]ethylamino]ethyl]trimethylammoniummethylsulfat Hydrogen[4-[[4-(diethylamino)phenyl][4-[ethyl(3-sulfonatobenzyl)amino]phenyl]methylen]cyclohexa-2,5-dien-1-yliden](ethyl)(3-sulfonatobenzyl)ammonium, Natriumsalz Disperse Blue 257 [2-[[4-[(2-Chlor-4-nitrophenyl)azo]phenyl]ethylamino]ethyl]trimethylammonium Reactive Blue BRF Disperse Violet 77 Disperse Scarlet SE-R Zinkbis(N-ethyl-N-phenyldithiocarbamat) Reactive Red ME-2G 4-(2-(N-PHENYL-N-ETHYLAMINO)ETHOXY)-3,5-DICHLOROBENZENAMINE Benzenamine, N-ethyl-4-nitro-N-nitroso- [2-[Ethyl[4-[(4-nitrophenyl)azo]phenyl]amino]ethyl]trimethylammoniumchlorid N-Ethylcyclohexanamin N-NITROSO-N-ETHYLANILINE N-(2-Chlorethyl)-N-ethylanilin Paquinimod Reactive Red 252 Trinatrium-5-[[4-chlor-6-(ethylphenylamino)-1,3,5-triazin-2-yl]amino]-4-hydroxy-3-[(2-sulfonatophenyl)azo]naphthalin-2,7-disulfonat
